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KMID : 0361020220650080461
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Korean Journal of Otolaryngology - Head and Neck Surgery
2022 Volume.65 No. 8 p.461 ~ p.466
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A Case of Sensorineural Hearing Loss Caused by Neurosyphilis in Patient Who Is Treated by Anti-Interleukin 17A Monoclonal Antibody
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Kim Dong-Gyu
Jung Da-Jung
Oh Min-Ji
Lee Kyu-Yup
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Abstract
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Syphilis is a sexually transmitted disease caused by Treponema pallidum, which can invadevarious organs. Syphilis can also cause otologic symptoms such as hearing impairment, tinnitusor dizziness and these otologic symptoms can occur at any stage of syphilis and can be associatedwith neurosyphilis. We report here a case of rapid progressive neurosyphilis showinghearing impairment in a patient with ankylosing spondylitis. He was treated with anti-interleukin17A monoclonal antibody. Since syphilis is one of the causes of reversible sensorineuralhearing loss and syphilis infection with immunosuppression can cause progressive hearingloss if patients in immunomodulatory therapy have sensorineural hearing loss, the possibilityof syphilis should be considered.
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KEYWORD
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Interleukin 17A, Neurosyphilis, Senorineural hearing loss, Syphilis
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